Studying the Bacterial Flagellar Motor using an Optical Torque Wrench
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چکیده
منابع مشابه
Mechanics of torque generation in the bacterial flagellar motor.
The bacterial flagellar motor (BFM) is responsible for driving bacterial locomotion and chemotaxis, fundamental processes in pathogenesis and biofilm formation. In the BFM, torque is generated at the interface between transmembrane proteins (stators) and a rotor. It is well established that the passage of ions down a transmembrane gradient through the stator complex provides the energy for torq...
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Many swimming bacteria are propelled by flagellar filaments driven by a rotary motor. Each of these tiny motors can generate an impressive torque. The motor torque vs. speed relationship is considered one of the most important measurable characteristics of the motor and therefore is a major criterion for judging models proposed for the working mechanism. Here we give an explicit explanation for...
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The optical torque wrench is a laser trapping technique that expands the capability of standard optical tweezers to torque manipulation and measurement, using the laser linear polarization to orient tailored microscopic birefringent particles. The ability to measure torque of the order of kBT (∼4 pN nm) is especially important in the study of biophysical systems at the molecular and cellular le...
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An electromechanical analysis Tim Elston Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, NM 87545 Alexander Mogilner Department of Mathematics, University of California, Davis, CA 95616 Aravi Samuel Department of Molecular & Cellular Biology, Harvard University, Cambridge, MA 02138 Rowland Institute for Science, Cambridge, MA 02142 George Oster Department of Molecular ...
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What do you think of the state of biology today? It has indeed changed in many ways, and to the good. Molecular biology has come into its own and provides enormous power to answer new and old questions in such areas as development, physiology, and cell biology. The use of mathematical tools has become increasingly effective in shedding light on ecological and evolutionary problems, and other ma...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.092